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MicroRNAs in Pathogenesis of Acute Kidney Injury

1 Jan 2016

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression mainly by repressing their target gene translation. A large spectrum of human diseases is associated with significant changes in miRNAs. Many miRNAs are induced in diseases, whereas some others are downregulated. The significance of miRNAs has been demonstrated in renal development and physiology, and in major kidney diseases such as acute...

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PMID: 27322758
DOI: 10.1159/000446551

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