No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels.

doi:10.1016/j.stemcr.2016.05.011

Article

No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels.

Stem cell reports - 14 Jun 2016

Sacchetti Benedetto, Funari Alessia, Remoli Cristina, Giannicola Giuseppe, Kogler Gesine, Liedtke Stefanie, Cossu Giulio, Serafini Marta, Sampaolesi Maurilio, Tagliafico Enrico, Tenedini Elena, Saggio Isabella, Robey Pamela G, Riminucci Mara, Bianco Paolo

Abstract excerpt

A widely shared view reads that mesenchymal stem/stromal cells ("MSCs") are ubiquitous in human connective tissues, can be defined by a common in vitro phenotype, share a skeletogenic potential as assessed by in vitro differentiation assays, and coincide with ubiquitous pericytes. Using stringent in vivo differentiation assays and transcriptome analysis, we show that human cell populations from different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels.

Abstract excerpt

Topics

Related research