Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector‐borne nematode diseases

Abstract excerpt

Neglected tropical diseases caused by parasitic nematodes inflict an immense health and socioeconomic burden throughout much of the developing world. Current estimates indicate that more than two billion people are infected with nematodes, resulting in the loss of 14 million disability-adjusted life years per annum. Although these parasites cause significant mortality, they primarily cause chronic morbidity...

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