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Article

Expression and Purification of Virus-like Particles for Vaccination

2 Jun 2016

Abstract excerpt

Virus-like particles (VLPs) and subviral particles (SVPs) are an alternative approach to viral vaccine design that offers the advantages of increased biosafety and stability over use of live pathogens. Non-infectious and self-assembling, VLPs are used to present structural proteins as immunogens, bypassing the need for live pathogens or recombinant viral vectors for antigen delivery. In this article, we...

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PMID: 27286040
DOI: 10.3791/54041

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