Article
Association of PINX1 but not TEP1 Polymorphisms with Progression to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Sriprapun Methee, Chuaypen Natthaya, Khlaiphuengsin Apichaya, Pinjaroen Nutcha, Payungporn Sunchai, Tangkijvanich Pisit
Abstract excerpt
Hepatocellular carcinoma (HCC) is major health problem with high mortality rates, especially in patients with hepatitis B virus (HBV) infection. Telomerase function is one of common mechanisms affecting genome stability and cancer development. Recent studies demonstrated that genetic polymorphisms of telomerase associated genes such as telomerase associated protein 1 (TEP1) rs1713449 and PIN2/TERF1-interacting...
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