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Article

The genetics of anxiety-related negative valence system traits.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2017

Savage Jeanne E, Sawyers Chelsea, Roberson-Nay Roxann, Hettema John M

Abstract excerpt

NIMH's Research Domain Criteria (RDoC) domain of negative valence systems (NVS) captures constructs of negative affect such as fear and distress traditionally subsumed under the various internalizing disorders. Through its aims to capture dimensional measures that cut across diagnostic categories and are linked to underlying neurobiological systems, a large number of phenotypic constructs have been proposed as...

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Identifiers

PMID: 27196537
DOI: 10.1002/ajmg.b.32459
PMCID: PMC5349709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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