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Article

Insulin resistance in prepubertal obese children correlates with sex-dependent early onset metabolomic alterations.

International journal of obesity (2005) - 1 Oct 2016

Mastrangelo A, Martos-Moreno G Á, García A, Barrios V, Rupérez F J, Chowen J A, Barbas C, Argente J

Abstract excerpt

BACKGROUND: Insulin resistance (IR) is usually the first metabolic alteration diagnosed in obese children and the key risk factor for development of comorbidities. The factors determining whether or not IR develops as a result of excess body mass index (BMI) are still not completely understood. OBJECTIVES: This study aimed to elucidate the mechanisms underpinning the predisposition toward hyperinsulinemia-related...

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Identifiers

PMID: 27163744
DOI: 10.1038/ijo.2016.92
PMCID: PMC5056960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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