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Article

Altered GABAA receptor expression in brainstem nuclei and SUDEP in Gabrg2(+/Q390X) mice associated with epileptic encephalopathy.

Epilepsy research - 1 Jul 2016

Xia Geqing, P Pourali Sarah, Warner Timothy A, Zhang Chun-Qing, L Macdonald Robert, Kang Jing-Qiong

Abstract excerpt

Sudden unexpected death in epilepsy (SUDEP) is the leading cause for death in individuals with epilepsy. The frequency of SUDEP correlates with the severity of epilepsies and lack of response to antiepileptic drug treatment, but the underlying mechanisms of SUDEP have not been elucidated fully. GABRG2(Q390X) is a mutation associated with the epileptic encephalopathy Dravet syndrome (DS) and with genetic epilepsy...

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Source

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Identifiers

PMID: 27131289
DOI: 10.1016/j.eplepsyres.2016.04.002
PMCID: PMC5433248

Genes

GABRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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