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Article

Combined Genotypic, Phylogenetic, and Epidemiologic Analyses of Mycobacterium tuberculosis Genetic Diversity in the Rhône Alpes Region, France.

PloS one - 1 Jan 2016

Pichat Catherine, Couvin David, Carret Gérard, Frédénucci Isabelle, Jacomo Véronique, Carricajo Anne, Boisset Sandrine, Dumitrescu Oana, Flandrois Jean-Pierre, Lina Gérard, Rastogi Nalin

Abstract excerpt

BACKGROUND: The present work relates to identification and a deep molecular characterization of circulating Mycobacterium tuberculosis complex (MTBC) strains in the Rhône-Alpes region, France from 2000 to 2010. It aimed to provide with a first snapshot of MTBC genetic diversity in conjunction with bacterial drug resistance, type of disease and available demographic and epidemiologic characteristics over an...

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PMID: 27128522
DOI: 10.1371/journal.pone.0153580
PMCID: PMC4851328

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