Article
Emergence of HCV resistance-associated variants in patients failing sofosbuvir-based regimens: an observational cohort.
Antiviral therapy - 1 Jan 2016
André-Garnier Elisabeth, Ribeyrol Olivier, Gournay Jerome, Besse Bernard, Coste-Burel Marianne, Mabille-Archambeaud Isabelle, Billaud Eric, Biron Charlotte, Pineau Solene, Raffi François, Imbert-Marcille Berthe-Marie
Abstract excerpt
BACKGROUND: Real-life effectiveness data of new hepatitis C direct-acting antivirals are now required. The present study aims to assess the rate of sustained viral response (SVR) and virological failure (VF) in patients infected with chronic HCV treated with sofosbuvir (SOF)-based regimens in routine medical practice. METHODS: This observational study included a total of 106 patients infected with HCV genotypes...
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