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Article

Early Detection of Epidemic GII-4 Norovirus Strains in UK and Malawi: Role of Surveillance of Sporadic Acute Gastroenteritis in Anticipating Global Epidemics.

PloS one - 1 Jan 2016

Allen David J, Trainor Eamonn, Callaghan Anna, O'Brien Sarah J, Cunliffe Nigel A, Iturriza-Gómara Miren

Abstract excerpt

Noroviruses are endemic in the human population, and are recognised as a leading cause of acute gastroenteritis worldwide. Although they are a highly diverse group of viruses, genogroup-II genotype-4 (GII-4) noroviruses are the most frequently identified strains worldwide. The predominance of GII-4 norovirus strains is driven by the periodic emergence of antigenic variants capable of evading herd protection. The...

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PMID: 27115152
DOI: 10.1371/journal.pone.0146972
PMCID: PMC4846118

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