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Article

Loss of function mutations in ATP2A2 and psychoses: A case report and literature survey.

Psychiatry and clinical neurosciences - 1 Aug 2016

Nakamura Takumi, Kazuno An-A, Nakajima Kazuo, Kusumi Ichiro, Tsuboi Takashi, Kato Tadafumi

Abstract excerpt

AIM: Though genetic factors play a major role in the pathophysiology of psychoses including bipolar disorder (BD) and schizophrenia, lack of well-established causative genetic mutations hampers their neurobiological studies. Darier's disease, an autosomal dominant skin disorder caused by mutations of ATP2A2 on chromosome 12q23-24.1, encoding sarco/endoplasmic reticulum calcium transporting ATPase 2 (SERCA2),...

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PMID: 27106560
DOI: 10.1111/pcn.12395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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