Article
Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36.
Journal of virology - 1 Jul 2016
Avey Denis, Tepper Sarah, Pifer Benjamin, Bahga Amritpal, Williams Hunter, Gillen Joseph, Li Wenwei, Ogden Sarah, Zhu Fanxiu
Abstract excerpt
UNLABELLED: Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of three human malignancies. KSHV ORF36 encodes a serine/threonine viral protein kinase, which is conserved throughout all herpesviruses. Although several studies have identified the viral and cellular substrates of conserved herpesvirus protein kinases (CHPKs), the precise functions of KSHV ORF36 during lytic replication remain...
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