Article
Clinical value of on-treatment HCV RNA levels during different sofosbuvir-based antiviral regimens.
Journal of hepatology - 1 Sept 2016
Maasoumy Benjamin, Vermehren Johannes, Welker Martin-Walter, Bremer Birgit, Perner Dany, Höner Zu Siederdissen Christoph, Deterding Katja, Lehmann Patrick, Cloherty Gavin, Reinhardt Birgit, Pawlotsky Jean-Michel, Manns Michael P, Zeuzem Stefan, Cornberg Markus, Wedemeyer Heiner, Sarrazin Christoph
Abstract excerpt
BACKGROUND & AIMS: The European Association for the Study of the Liver (EASL) guidelines recommend HCV RNA measurements at specific time points during sofosbuvir(SOF)-therapy. However, it remains unclear, how these results should be interpreted. We aimed to analyze whether on-treatment HCV RNA levels predict relapse comparing the CobasAmpliPrep/CobasTaqMan v2.0 (CAP/CTM) and Abbott RealTime HCV (ART) assays....
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