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Article

Ciliate Paramecium is a natural reservoir of Legionella pneumophila.

Scientific reports - 15 Apr 2016

Watanabe Kenta, Nakao Ryo, Fujishima Masahiro, Tachibana Masato, Shimizu Takashi, Watarai Masahisa

Abstract excerpt

Legionella pneumophila, the causative agent of Legionnaires' disease, replicates within alveolar macrophages and free-living amoebae. However, the lifestyle of L. pneumophila in the environment remains largely unknown. Here we established a novel natural host model of L. pneumophila endosymbiosis using the ciliate Paramecium caudatum. We also identified Legionella endosymbiosis-modulating factor A (LefA), which...

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Share to Legionella pneumophila
Share to Disease Reservoirs
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Legionnaires' Disease

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Identifiers

PMID: 27079173
DOI: 10.1038/srep24322
PMCID: PMC4832178

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