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Anti-apoptotic response during anoxia and recovery in a freeze-tolerant wood frog (Rana sylvatica)

24 Mar 2016

Abstract excerpt

The common wood frog, Rana sylvatica, utilizes freeze tolerance as a means of winter survival. Concealed beneath a layer of leaf litter and blanketed by snow, these frogs withstand subzero temperatures by allowing approximately 65-70% of total body water to freeze. Freezing is generally considered to be an ischemic event in which the blood oxygen supply is impeded and may lead to low levels of ATP production and...

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PMID: 27042393
DOI: 10.7717/peerj.1834

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