Article
Allogeneic Stem Cell Transplantation for Patients with T315I BCR-ABL Mutated Chronic Myeloid Leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Jun 2016
Xu Lan-Ping, Xu Zheng-Li, Zhang Xiao-Hui, Chen Huan, Chen Yu-Hong, Han Wei, Chen Yao, Wang Feng-Rong, Wang Jing-Zhi, Wang Yu, Yan Chen-Hua, Mo Xiao-Dong, Liu Kai-Yan, Huang Xiao-Jun
Abstract excerpt
Allogeneic stem cell transplantation (SCT) is currently the only curative treatment option for chronic myeloid leukemia (CML) patients with BCR-ABL T315I mutations. We report the outcome of SCT in 22 patients with T315I(+) CML, most (n = 16) from haploidentical family donors (HID-SCT). At the time the mutation was detected, 8 patients were in the chronic phase (CP), 7 in the accelerated phase (AP), and 7 in the...
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