Article
CD14 is associated with biliary stricture formation.
Hepatology (Baltimore, Md.) - 1 Sept 2016
Friedrich Kilian, Smit Mark, Brune Maik, Giese Thomas, Rupp Christian, Wannhoff Andreas, Kloeters Petra, Leopold Yvonne, Denk Gerald Ulrich, Weiss Karl Heinz, Stremmel Wolfgang, Sauer Peter, Hohenester Simon, Schirmacher Peter, Schemmer Peter, Gotthardt Daniel Nils
Abstract excerpt
UNLABELLED: The pathogenesis of intrahepatic biliary stricture formation in patients with primary sclerosing cholangitis (PSC) or after liver transplantation (LTx) remains elusive. CD14 receptor signaling is a key mediator of the innate immune system; its common genetic variant is associated with alcoholic liver disease. PSC and LTx cohort patients and primary biliary cirrhosis (PBC) control patients were...
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