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Article

Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis

8 Mar 2016

Abstract excerpt

Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa. Over the last decade, concerted control efforts have reduced reported cases to below 10,000 annually, bringing complete elimination within reach. A potential technology to eliminate HAT involves rendering the flies resistant to trypanosome infection. This...

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PMID: 26954675
DOI: 10.1371/journal.pntd.0004465

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