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Article

Evaluating Paratransgenesis as a Potential Control Strategy for African Trypanosomiasis

15 Aug 2013

Abstract excerpt

Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this approach involves modification of the commensal symbiotic bacteria Sodalis to express trypanosome-resistance-conferring products. Modified Sodalis can then be...

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PMID: 23967363
DOI: 10.1371/journal.pntd.0002374

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