Article
Low-grade and anaplastic oligodendroglioma.
Handbook of clinical neurology - 1 Jan 2016
Van Den Bent Martin J, Bromberg Jacolien E C, Buckner Jan
Abstract excerpt
Anaplastic oligodendrogliomas have long attracted interest because of their sensitivity to chemotherapy, in particular in the subset of 1p/19q co-deleted tumors. Recent molecular studies have shown that all 1p/19q co-deleted tumors have IDH mutations and most of them also have TERT mutations. Because of the presence of similar typical genetic alterations in astrocytoma and glioblastoma, the current trend is to...
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