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Article

Impairment of Vision in a Mouse Model of Usher Syndrome Type III.

Investigative ophthalmology & visual science - 1 Mar 2016

Tian Guilian, Lee Richard, Ropelewski Philip, Imanishi Yoshikazu

Abstract excerpt

PURPOSE: The purpose of this study was to obtain an Usher syndrome type III mouse model with retinal phenotype. METHODS: Speed congenic method was used to obtain Clrn1 exon 1 knockout (Clrn1-/-) and Clrn1N48K knockin (Clrn1N48K/N48K) mice under A/J background. To study the retinal functions of these mice, we measured scotopic and photopic ERG responses. To observe if there are any structural abnormalities, we...

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Source

Identifiers

PMID: 26943149
DOI: 10.1167/iovs.15-16946

Genes

ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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