Article
Prevalence and phenotypic correlations of EIF1AX mutations in thyroid nodules.
Endocrine-related cancer - 1 Apr 2016
Karunamurthy Arivarasan, Panebianco Federica, J Hsiao Susan, Vorhauer Jennie, Nikiforova Marina N, Chiosea Simion, Nikiforov Yuri E
Abstract excerpt
The EIF1AX gene mutations have been recently found in papillary thyroid carcinoma (PTC) and anaplastic thyroid carcinoma (ATC). The prevalence of these mutations in other types of thyroid cancers and benign nodules is unknown. In this study, we analyzed the occurrence of EIF1AX mutations in exons 2, 5, and 6 of the gene in a series of 266 thyroid tumors and hyperplastic nodules by either Sanger or next-generation...
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