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Investigation of a suspected nosocomial transmission of blaKPC3-mediated carbapenem-resistant Klebsiella pneumoniae by whole genome sequencing.

Diagnostic microbiology and infectious disease - 1 Apr 2016

Yang Shangxin, Hemarajata Peera, Hindler Janet, Ward Kevin, Adisetiyo Helty, Li Fan, Aldrovandi Grace M, Green Nicole M, Russell Dana, Rubin Zachary, Humphries Romney M

Abstract excerpt

Whole genome sequencing (WGS) was compared to pulse-field gel electrophoresis (PFGE) of XbaI-digested genomic DNA, as methods by which to evaluate a potential transmission of carbapenem-resistant Klebsiella pneumoniae between 2 hospital inpatients. PFGE result demonstrated only 1-band difference between the isolates, suggesting probable relatedness. In contrast, while WGS data demonstrated the same sequence type...

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PMID: 26867964
DOI: 10.1016/j.diagmicrobio.2015.12.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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