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Article

Basic FGF or VEGF gene therapy corrects insufficiency in the intrinsic healing capacity of tendons

11 Feb 2016

Abstract excerpt

Tendon injury during limb motion is common. Damaged tendons heal poorly and frequently undergo unpredictable ruptures or impaired motion due to insufficient innate healing capacity. By basic fibroblast growth factor (bFGF) or vascular endothelial growth factor (VEGF) gene therapy via adeno-associated viral type-2 (AAV2) vector to produce supernormal amount of bFGF or VEGF intrinsically in the tendon, we...

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PMID: 26865366
DOI: 10.1038/srep20643

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