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Article

Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution.

Scientific reports - 11 Feb 2016

Fernández-Sampedro Miguel A, Invergo Brandon M, Ramon Eva, Bertranpetit Jaume, Garriga Pere

Abstract excerpt

Visual rhodopsins are membrane proteins that function as light photoreceptors in the vertebrate retina. Specific amino acids have been positively selected in visual pigments during mammal evolution, which, as products of adaptive selection, would be at the base of important functional innovations. We have analyzed the top candidates for positive selection at the specific amino acids and the corresponding reverse...

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PMID: 26865329
DOI: 10.1038/srep21570
PMCID: PMC4749998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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