Article
Identification of new candidate drugs for lung cancer using chemical-chemical interactions, chemical-protein interactions and a K-means clustering algorithm.
Journal of biomolecular structure & dynamics - 1 Jan 2016
Lu Jing, Chen Lei, Yin Jun, Huang Tao, Bi Yi, Kong Xiangyin, Zheng Mingyue, Cai Yu-Dong
Abstract excerpt
Lung cancer, characterized by uncontrolled cell growth in the lung tissue, is the leading cause of global cancer deaths. Until now, effective treatment of this disease is limited. Many synthetic compounds have emerged with the advancement of combinatorial chemistry. Identification of effective lung cancer candidate drug compounds among them is a great challenge. Thus, it is necessary to build effective...
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