Article
Host manipulation by cancer cells: Expectations, facts, and therapeutic implications.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Mar 2016
Tissot Tazzio, Arnal Audrey, Jacqueline Camille, Poulin Robert, Lefèvre Thierry, Mery Frédéric, Renaud François, Roche Benjamin, Massol François, Salzet Michel, Ewald Paul, Tasiemski Aurélie, Ujvari Beata, Thomas Frédéric
Abstract excerpt
Similar to parasites, cancer cells depend on their hosts for sustenance, proliferation and reproduction, exploiting the hosts for energy and resources, and thereby impairing their health and fitness. Because of this lifestyle similarity, it is predicted that cancer cells could, like numerous parasitic organisms, evolve the capacity to manipulate the phenotype of their hosts to increase their own fitness. We claim...
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