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Article

Immunomodulatory and Anti-Inflammatory Activities of Chicken Cathelicidin-2 Derived Peptides.

PloS one - 1 Jan 2016

van Dijk Albert, van Eldik Mandy, Veldhuizen Edwin J A, Tjeerdsma-van Bokhoven Hanne L M, de Zoete Marcel R, Bikker Floris J, Haagsman Henk P

Abstract excerpt

Host Defence Peptides and derived peptides are promising classes of antimicrobial and immunomodulatory lead compounds. For this purpose we examined whether chicken cathelicidin-2 (CATH-2)-derived peptides modulate the function and inflammatory response of avian immune cells. Using a chicken macrophage cell line (HD11) we found that full-length CATH-2 dose-dependently induced transcription of chemokines...

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Identifiers

PMID: 26848845
DOI: 10.1371/journal.pone.0147919
PMCID: PMC4743981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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