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Article

Temperament and externalizing behavior as mediators of genetic risk on adolescent substance use.

Journal of abnormal psychology - 1 May 2016

Trucco Elisa M, Hicks Brian M, Villafuerte Sandra, Nigg Joel T, Burmeister Margit, Zucker Robert A

Abstract excerpt

Understanding how specific genes contribute to risk for addiction remains challenging. This study tests whether childhood temperament and externalizing behavior in early adolescence account for a portion of the association between specific genetic variants and substance use problems in late adolescence. The sample consisted of 487 adolescents from the Michigan Longitudinal Study, a high-risk sample (70.2% male,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Norepinephrine Plasma Membrane Transport Proteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 26845260
DOI: 10.1037/abn0000143
PMCID: PMC4850114

Genes

DRD4
GABRA2
GABRA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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