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Article

Autism and Cancer Share Risk Genes, Pathways, and Drug Targets.

Trends in genetics : TIG - 1 Mar 2016

Crawley Jacqueline N, Heyer Wolf-Dietrich, LaSalle Janine M

Abstract excerpt

Autism is a neurodevelopmental disorder, diagnosed behaviorally by social and communication deficits, repetitive behaviors, and restricted interests. Recent genome-wide exome sequencing has revealed extensive overlap in risk genes for autism and for cancer. Understanding the genetic commonalities of autism(s) and cancer(s), with a focus on mechanistic pathways, could lead to repurposed therapeutics.

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Identifiers

PMID: 26830258
DOI: 10.1016/j.tig.2016.01.001
PMCID: PMC4769654

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