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Article

Analysis and application of ATP7B gene mutations in 35 patients with hepatolenticular degeneration.

Genetics and molecular research : GMR - 29 Dec 2015

Zong Y N, Kong X D

Abstract excerpt

We investigated the genetic mutations involved in Wilson's disease to improve prenatal genetic diagnosis and presymptomatic diagnosis. The polymerase chain reaction (PCR) was used to amplify the exons and exon-intron boundaries of the ATP7B gene in 35 Wilson's disease pedigrees. The PCR products were further analyzed by Sanger sequencing. Prenatal genetic diagnoses were performed by chorionic villus sampling...

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PMID: 26782526
DOI: 10.4238/2015.December.28.25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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