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Article

Potential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?

14 Jan 2016

Abstract excerpt

Underneath the intricacy of every cancer lies mysterious events that impel the tumour cell and its posterity into abnormal growth and tissue invasion. Oncogenic mutations disturb the regulatory circuits responsible for the governance of versatile cellular functions, permitting tumour cells to endure deregulated proliferation, resist to proapoptotic insults, invade and erode normal tissues and above all escape...

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Identifiers

PMID: 26775709
DOI: 10.1038/cddis.2015.275

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