Article
Assessment of Background Parenchymal Enhancement and Lesion Kinetics in Breast MRI of BRCA 1/2 Mutation Carriers Compared to Matched Controls Using Quantitative Kinetic Analysis.
Academic radiology - 1 Mar 2016
Lewin Alana A, Kim Sungheon Gene, Babb James S, Melsaether Amy N, McKellop Jason, Moccaldi Melanie, Klautau Leite Ana Paula, Moy Linda
Abstract excerpt
RATIONALE AND OBJECTIVES: To investigate whether quantitative kinetic analysis of lesions and background parenchyma in breast magnetic resonance imaging can elucidate differences between BRCA carriers and sporadic controls with high risk for breast cancer. MATERIALS AND METHODS: Fifty-nine BRCA and 59 control cases (49 benign, 10 malignant) were examined in this study. Principal component analysis was applied for...
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