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Article

Phylogeny, resistome and mobile genetic elements of emergent OXA-48 and OXA-245 Klebsiella pneumoniae clones circulating in Spain.

The Journal of antimicrobial chemotherapy - 1 Apr 2016

Pérez-Vázquez María, Oteo Jesús, García-Cobos Silvia, Aracil Belén, Harris Simon R, Ortega Adriana, Fontanals Dionisia, Hernández Juan Manuel, Solís Sonia, Campos José, Dougan Gordon, Kingsley Robert A

Abstract excerpt

OBJECTIVES: The global emergence of OXA-48-producing Klebsiella pneumoniae clones is a significant threat to public health. We used WGS and phylogenetic analysis of Spanish isolates to investigate the population structure of blaOXA-48-like-expressing K. pneumoniae ST11 and ST405 and to determine the distribution of resistance genes and plasmids encoding blaOXA-48-like carbapenemases. METHODS: SNPs identified in...

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PMID: 26769896
DOI: 10.1093/jac/dkv458
PMCID: PMC4790626

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