Article
Privacy-preserving genomic testing in the clinic: a model using HIV treatment.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Aug 2016
McLaren Paul J, Raisaro Jean Louis, Aouri Manel, Rotger Margalida, Ayday Erman, Bartha István, Delgado Maria B, Vallet Yannick, Günthard Huldrych F, Cavassini Matthias, Furrer Hansjakob, Doco-Lecompte Thanh, Marzolini Catia, Schmid Patrick, Di Benedetto Caroline, Decosterd Laurent A, Fellay Jacques, Hubaux Jean-Pierre, Telenti Amalio
Abstract excerpt
PURPOSE: The implementation of genomic-based medicine is hindered by unresolved questions regarding data privacy and delivery of interpreted results to health-care practitioners. We used DNA-based prediction of HIV-related outcomes as a model to explore critical issues in clinical genomics. METHODS: We genotyped 4,149 markers in HIV-positive individuals. Variants allowed for prediction of 17 traits relevant to...
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