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Article

Natural course of congenital hypothyroidism by dual oxidase 2 mutations from the neonatal period through puberty.

European journal of endocrinology - 1 Apr 2016

Maruo Yoshihiro, Nagasaki Keisuke, Matsui Katsuyuki, Mimura Yu, Mori Asami, Fukami Maki, Takeuchi Yoshihiro

Abstract excerpt

AIM: We previously reported that biallelic mutations in dual oxidase 2 (DUOX2) cause transient hypothyroidism. Since then, many cases with DUOX2 mutations have been reported. However, the clinical features and prognosis of individuals with DUOX2 defects have not been clarified. OBJECTIVE: We investigated the prognosis of patients with congenital hypothyroidism (CH) due to DUOX2 mutations. PATIENTS: Twenty-five...

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Source

Identifiers

PMID: 26742565
DOI: 10.1530/EJE-15-0959

Genes

DUOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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