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Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus: Does Vancomycin Heteroresistance Matter?

Antimicrobial agents and chemotherapy - 4 Jan 2016

Claeys Kimberly C, Lagnf Abdalhamid M, Hallesy Jessica A, Compton Matthew T, Gravelin Alison L, Davis Susan L, Rybak Michael J

Abstract excerpt

Vancomycin remains the mainstay treatment for methicillin-resistant Staphylococcus aureus (MRSA) infections, including pneumonia. There is concern regarding the emergence of vancomycin tolerance, caused by heterogeneous vancomycin-intermediate S. aureus (hVISA), and subsequent vancomycin treatment failure. Pneumonia is associated with high morbidity and mortality, especially with delays in appropriate therapy....

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Identifiers

PMID: 26729497
DOI: 10.1128/AAC.02388-15
PMCID: PMC4775950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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