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Article

Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.

International journal of molecular sciences - 7 Dec 2015

Hofmann-Apitius Martin, Ball Gordon, Gebel Stephan, Bagewadi Shweta, de Bono Bernard, Schneider Reinhard, Page Matt, Kodamullil Alpha Tom, Younesi Erfan, Ebeling Christian, Tegnér Jesper, Canard Luc

Abstract excerpt

Since the decoding of the Human Genome, techniques from bioinformatics, statistics, and machine learning have been instrumental in uncovering patterns in increasing amounts and types of different data produced by technical profiling technologies applied to clinical samples, animal models, and cellular systems. Yet, progress on unravelling biological mechanisms, causally driving diseases, has been limited, in part...

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PMID: 26690135
DOI: 10.3390/ijms161226148
PMCID: PMC4691095

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