Correlation between oxidative stress and the NF-κB signaling pathway in the pulmonary tissues of obese asthmatic mice

Abstract excerpt

The obesity-asthma phenotype is characterized by increased asthma severity and decreased glucocorticoid responsiveness. To date, the mechanism underlying the association between obesity and asthma remain to be fully elucidated. The present study investigated the correlation between oxidative stress and the nuclear factor (NF)-κB pathway in obese asthmatic mice. The animals were divided into the following groups:...

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• Share to Adipokines, Inflammation, and Metabolic Diseases
• Share to Asthma and respiratory diseases
• Share to Genomics, phytochemicals, and oxidative stress