Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits.

Obesity (Silver Spring, Md.) - 1 Jan 2016

Brune Jakob E, Kern Matthias, Kunath Anne, Flehmig Gesine, Schön Michael R, Lohmann Tobias, Dressler Miriam, Dietrich Arne, Fasshauer Mathias, Kovacs Peter, Stumvoll Michael, Blüher Matthias, Klöting Nora

Abstract excerpt

OBJECTIVE: Independent previous studies in both rodents and humans suggest a role of developmental genes in the origin of obesity and body fat distribution. Here, the hypothesis that human adipose tissue (AT) expression of the developmental genes homeobox transcription factors C9 (HOXC9) and C10 (HOXC10) is fat depot-specific and related to obesity-related traits was tested. METHODS: In 636 individuals, HOXC9 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abdomen
Share to Adipocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adipose Tissue

Share to Body Fat Distribution

Share to Gene Expression

Share to Homeodomain Proteins

Share to Obesity

Share to Phenotype

Source

Identifiers

PMID: 26647900
DOI: 10.1002/oby.21317

Genes

HOXC10
HOXC9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits.PMID 26647900Read ↗

Distinct Developmental Signatures of Human Abdominal and Gluteal Subcutaneous Adipose Tissue DepotsSemantic proximity Read ↗

Evidence for a role of developmental genes in the origin of obesity and body fat distributionSemantic proximity Read ↗

Integrative Analysis Revealing Human Adipose-Specific Genes and Consolidating Obesity LociSemantic proximity Read ↗

The HOX genes network in metabolic diseasesSemantic proximity Read ↗

Gene expression regional differences in human subcutaneous adipose tissueSemantic proximity Read ↗

Obesity phenotypes: depot-differences in adipose tissue and their clinical implications.Semantic proximity Read ↗

Epigenetic Regulation of Depot-Specific Gene Expression in Adipose TissueSemantic proximity Read ↗

Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic ComplicationsSemantic proximity Read ↗

Adipose Depots Possess Unique Developmental Gene SignaturesSemantic proximity Read ↗

Differential open chromatin profile and transcriptomic signature define depot-specific human subcutaneous preadipocytes: primary outcomesSemantic proximity Read ↗

Comparative transcriptome analysis reveals potentially novel roles of Homeobox genes in adipose deposition in fat-tailed sheep.Semantic proximity Read ↗

The Transcription Factor HOXA5: Novel Insights into Metabolic Diseases and Adipose Tissue DysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.