Article
POLYPRENOL REDUCTASE2 Deficiency Is Lethal in Arabidopsis Due to Male Sterility.
The Plant cell - 1 Dec 2015
Jozwiak Adam, Gutkowska Malgorzata, Gawarecka Katarzyna, Surmacz Liliana, Buczkowska Anna, Lichocka Malgorzata, Nowakowska Julita, Swiezewska Ewa
Abstract excerpt
Dolichol is a required cofactor for protein glycosylation, the most common posttranslational modification modulating the stability and biological activity of proteins in all eukaryotic cells. We have identified and characterized two genes, PPRD1 and -2, which are orthologous to human SRD5A3 (steroid 5α reductase type 3) and encode polyprenol reductases responsible for conversion of polyprenol to dolichol in...
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