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Article

Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism.

Scientific reports - 9 Nov 2015

Maekawa Motoko, Iwayama Yoshimi, Ohnishi Tetsuo, Toyoshima Manabu, Shimamoto Chie, Hisano Yasuko, Toyota Tomoko, Balan Shabeesh, Matsuzaki Hideo, Iwata Yasuhide, Takagai Shu, Yamada Kohei, Ota Motonori, Fukuchi Satoshi, Okada Yohei, Akamatsu Wado, Tsujii Masatsugu, Kojima Nobuhiko, Owada Yuji, Okano Hideyuki, Mori Norio, Yoshikawa Takeo

Abstract excerpt

The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. During fetal and postnatal periods of development, the growing brain requires a reliable supply of fatty acids. Because autism spectrum disorders (ASD) are now recognized as disorders caused by impaired early brain development, it is possible that functional abnormalities of SLC27A genes may...

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PMID: 26548558
DOI: 10.1038/srep16239
PMCID: PMC4637822

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