Article
Linkage Analysis of Genomic Regions Contributing to the Expression of Type 1 Diabetes Microvascular Complications and Interaction with HLA.
Journal of diabetes research - 1 Jan 2015
Lipner Ettie M, Tomer Yaron, Noble Janelle A, Monti Maria C, Lonsdale John T, Corso Barbara, Greenberg David A
Abstract excerpt
We conducted linkage analysis to follow up earlier work on microvascular complications of type 1 diabetes (T1D). We analyzed 415 families (2,008 individuals) previously genotyped for 402 SNP markers spanning chromosome 6. We did linkage analysis for the phenotypes of retinopathy and nephropathy. For retinopathy, two linkage peaks were mapped: one located at the HLA region and another novel locus telomeric to HLA....
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