Article
Mucosal alpha-papillomaviruses are not associated with esophageal squamous cell carcinomas: Lack of mechanistic evidence from South Africa, China and Iran and from a world-wide meta-analysis.
International journal of cancer - 1 Jul 2016
Halec Gordana, Schmitt Markus, Egger Sam, Abnet Christian C, Babb Chantal, Dawsey Sanford M, Flechtenmacher Christa, Gheit Tarik, Hale Martin, Holzinger Dana, Malekzadeh Reza, Taylor Philip R, Tommasino Massimo, Urban Margaret I, Waterboer Tim, Pawlita Michael, Sitas Freddy
Abstract excerpt
Epidemiological and mechanistic evidence on the causative role of human papillomaviruses (HPV) in esophageal squamous cell carcinoma (ESCC) is unclear. We retrieved alcohol- and formalin-fixed paraffin-embedded ESCC tissues from 133 patients seropositive for antibodies against HPV early proteins, from high-incidence ESCC regions: South Africa, China and Iran. With rigorous care to prevent nucleic acid...
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