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Article

Proteomic profiling of host-biofilm interactions in an oral infection model resembling the periodontal pocket

3 Nov 2015

Abstract excerpt

Periodontal infections cause inflammatory destruction of the tooth supporting tissues. We recently developed a dynamic, in vitro periodontal organotypic tissue model in a perfusion bioreactor system, in co-culture with an 11-species subgingival biofilm, which may recapitulate early events during the establishment of periodontal infections. This study aimed to characterize the global proteome regulations in this...

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PMID: 26525412
DOI: 10.1038/srep15999

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