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Type-specific PCR assays for Babesia bovis msa-1 genotypes in Asia: Revisiting the genetic diversity in Sri Lanka, Mongolia, and Vietnam.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2016

Liyanagunawardena Nilukshi, Sivakumar Thillaiampalam, Kothalawala Hemal, Silva Seekkuge Susil Priyantha, Battsetseg Badgar, Lan Dinh Thi Bich, Inoue Noboru, Igarashi Ikuo, Yokoyama Naoaki

Abstract excerpt

Babesia bovis is the most virulent Babesia organism, resulting in a high mortality rate in cattle. The genetic diversity of B. bovis merozoite surface antigens (MSAs), such as MSA-1, MSA-2b, and MSA-2c, might be linked to altered immune profiles in the host animals. The present study aimed to develop type-specific PCR assays for Asian msa-1 genotypes, thereby re-analyzing the genetic diversity of msa-1 in Sri...

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PMID: 26520797
DOI: 10.1016/j.meegid.2015.10.029

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