Article
Factors influencing the efficacy of rilpivirine in HIV-1 subtype C in low- and middle-income countries.
The Journal of antimicrobial chemotherapy - 1 Feb 2016
Neogi Ujjwal, Häggblom Amanda, Singh Kamalendra, Rogers Leonard C, Rao Shwetha D, Amogne Wondwossen, Schülter Eugen, Zazzi Maurizio, Arnold Eddy, Sarafianos Stefan G, Sönnerborg Anders
Abstract excerpt
OBJECTIVES: The use of the NNRTI rilpivirine in low- and middle-income countries (LMICs) is under debate. The main objective of this study was to provide further clinical insights and biochemical evidence on the usefulness of rilpivirine in LMICs. PATIENTS AND METHODS: Rilpivirine resistance was assessed in 5340 therapy-naive and 13,750 first-generation NNRTI-failed patients from Europe and therapy-naive HIV-1...
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