Article
Pseudomonas aeruginosa displays an altered phenotype in vitro when grown in the presence of mannitol.
British journal of biomedical science - 1 Jan 2015
Moore J E, Rendall J C, Downey D G
Abstract excerpt
D-mannitol has been approved in dry powder formulation as an effective antimucolytic agent in patients with cystic fibrosis. What is not known is the effect of adding a metabolisable sugar on the biology of chronic bacterial pathogens in the CF lung. Therefore, a series of simple in vitro experiments were performed to examine the effect of adding D-mannitol on the phenotype of the CF respiratory pathogens...
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