Article
The RNA helicase, eIF4A-1, is required for ovule development and cell size homeostasis in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Dec 2015
Bush Maxwell S, Crowe Natalie, Zheng Tao, Doonan John H
Abstract excerpt
eIF4A is a highly conserved RNA-stimulated ATPase and helicase involved in the initiation of mRNA translation. The Arabidopsis genome encodes two isoforms, one of which (eIF4A-1) is required for the coordination between cell cycle progression and cell size. A T-DNA mutant eif4a1 line, with reduced eIF4A protein levels, displays slow growth, reduced lateral root formation, delayed flowering and abnormal ovule...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Cell Cycle
- Cell Size
- Eukaryotic Initiation Factor-4A
- Flowers
- Genome, Plant
- Homeostasis
- Meristem
- Mitosis
- Mutation
- Ovule
- Plant Roots
- Protein Isoforms